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Review of 'Rabid' on 'Goodreads'

4 stars

This is the second book focussing on viruses (and more specific on zoonotic diseases) I've read this year, the first being Richard Preston's excellent The Hot Zone.

While Preston focuses his story on the scientific side of Ebola and a specific (possible) outbreak of the virus in the US the approach of Rabid is much broader. But that may not be too surprising, given that Ebola itself is the new kid on the zoonotic block. Especially compared to Rabies, one of the oldest known zoonotic pathogens with over 5000 years of written history about it.
Rabid starts of with the first still known cases of Rabies-descriptions in literature and how people in ancient times tried to battle the fatal infection (which is so much fun to read, preparare to learn about proto-waterboarding and the rooster's anus!). It goes on to how Rabies transformed our culture and was at least partially an inspiration for myths about werewolves, vampires (and of course, in more recent times: Zombies!) and how Pasteur went on to get a vaccine for the disease.
The last couple of chapter are on modern medicine: How outbreaks of Rabies in animal populations are controlled, different ideas on how the disease can may be cured if the vaccine failed (or wasn't there in the first place…) and even more fun: How proteins found in Rabies might be someday useful to deliver drugs to the brain, which is ± impossible today due to the lockdown imposed by the blood-brain-barrier.

Fun and quick to read, even if the beginning might make you paranoid of contracting a nearly always fatal disease. In exchange for being scared senseless you will learn a lot of medical & cultural history and modern medicine. That's a fair tradeoff to me.