Mostly from the author's personally-involved-lab-science perspective, focused history of gene editing, specific tech capabilities with CRISPR, and societal implications of a tool this accurate and cheap. Author is making a serious effort to speak publicly beyond the scientific community about potential rules and implications, in general she sees plant/animal modifications as obvious (wheat, pork - already fully/exclusively domesticated species), is worried about germline / gene drive changes to wild populations (mosquitoes, say), and thinks we need an Asilomar-like global ban on human germline modifications until we know more.