More than being propelled by a coherent plot, Gyo is driven by its action. Our protagonist is pulled from one situation to the next as the world gives way to a marine apocalypse.

It lacks a lot of what made Uzumaki so disturbing. You don't have that teleological unraveling of reality. Gyo is a lot more pedestrian in its horror, but that's also what makes it fun. It's kind of Dawn of the Dead with fish.