BookWyrm

PLOS Biology

Which neural circuits allow memory retrieval to influence behaviors? This study shows how #fear #memory activation initiates & sustains #FreezingBehavior in mice via the interplay of #norepinephrine & activation of different prefrontal #neuron subtypes @PLOSBiology https://plos.io/3TGqt7a

Top: Representative images showing the spatial localization of labeled dmPFC neurons with BFP (blue) or retrobeads (red), taken using 10 X (upper) or 40 X (lower) objectives. The majority of labelled neurons were located in layer II/III of dmPFC. Scale bars, 100 μm (10 X) and 25 μm (40 X). Bottom: Summary on the neural circuit mediating the transition from memory retrieval to freezing behavior. Presentation of CS+ activates LA neurons and TeA neurons. The activated LA neurons activate dmPFC T-neurons, which in turn activate dmPFC S-neurons and LC neurons. S-neurons receive inputs from TeA and send their outputs to BLA, which projects to PAG to enable freezing behavior. Activated LC neurons release NE in the dmPFC via their projections.

PLOS Biology

Ganglioside GM2 accumulation can lead to #TaySachsDisease & #SandhoffDisease. This study develops a new, in vitro, #neuron -based model of GM2 #gangliosidosis, revealing changes in protein & lipid composition of the plasma membrane that impact neuronal firing @PLOSBiology https://plos.io/45UMBlt

Top left: Fluorescence microscopy images of neurons stained for β3-tubulin (white), LAMP1 for lysosomes (red), GM2 (green) and DAPI (blue). GM2 positive puncta were quantified and analyzed for co-localization with lysosomes. Scale bar (white line) represents 20 μm. Top right:. Transmission electron microscopy images of SCRM, ΔHEXA and ΔHEXB CRISPRi cell lines. Zoomed images are shown to illustrate membrane whorls and zebra bodies in enlarged lysosomes. Scale bar (white line) represents 500 nm. Right: Schematic diagram of the GM2 ganglioside detailing the composition of the glycan headgroup and illustrating which bond is cleaved by the HexA enzyme (red dotted line).

Pixelcats⁷

Ok so after a few listens, the whole EP is amazing, and we're not surprised it's this good at all. My faves for the day are Neuron and i wonder - it's hard to resist looping them for the next few hours.

Congratulations to our sunshine boy - he's done it again. And all hail master Producer Pdogg who is equally magical!

Streaming playlist is ready .. let's gooo!

https://open.spotify.com/playlist/1CoPQPPPxRcy6er6ETPuK6?si=22076f6322dd436c

#JHope #Neuron #OnTheStreet #JHopeOnTheStreet #Pdogg #BTS #FediArmy

Julien Deswaef quoted Rage Inside the Machine by Robert Elliott Smith

Robert Elliott Smith: Rage Inside the Machine (2019, Bloomsbury Publishing Plc)

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We live in a world increasingly ruled by technology; we seem as governed by technology …

In 1981, the AI researcher and Yale University professor Drew McDermott called this practice of naming computational phenomena with words denoting human characteristics and capabilities wishful mnemonics. He suggested that technologists' use of such words reflected a deep-seated desire for the computational objects in question to magically assume the human-like qualities being described.

— Rage Inside the Machine by Robert Elliott Smith (Page 208 - 209)

#AI #GenAI #neuron #intelligence #learning

Michele Banks

Sale! Save 40% on this gorgeous silk #neuron scarf #sciart #fedigiftshop https://artologica.etsy.com/listing/575478105

pale blue silk scarf with black neuron drawing

Surly Amy

Another new neuron painting. #sfn23 #neuron #art #painting

Surly Amy

#neuron necklaces in their baby form.

PLOS Biology

How do new #TasteBud cells connect with a taste ganglion #neuron? @ZacharyWhiddon1 @Krimmlab &co use in vivo 2-photon microscopy to observe motility & branching of taste axon arbors, revealing remarkable structural plasticity in taste buds #PLOSBiology https://plos.io/3PlIRAH

Dr. Eingekochtes Wasser

Faszinierende Größenverhältnisse

#Haar #Neuron #Bakterien #Viren

Video credits: MetaBallStudios